26 research outputs found

    A Prague Markup Language profile for the SemTi-Kamols grammar model

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    Proceedings of the 18th Nordic Conference of Computational Linguistics NODALIDA 2011. Editors: Bolette Sandford Pedersen, Gunta Nešpore and Inguna Skadiņa. NEALT Proceedings Series, Vol. 11 (2011), 303-306. © 2011 The editors and contributors. Published by Northern European Association for Language Technology (NEALT) http://omilia.uio.no/nealt . Electronically published at Tartu University Library (Estonia) http://hdl.handle.net/10062/1695

    Sars-COV-2 Vaccination DID Not Affect the Clinical Course of IGA Nephropathy in Latvian Adult Cohort

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    BACKGROUND AND AIMS: The current strategy to fight against the COVID-19 pandemic involves active patient vaccination. Patients with renal and autoimmune diseases are in high risk for severe COVID-19 infection [1]. Therefore they should be prioritized for vaccination. Immunoglobulin A nephropathy (IgAN) is one of the most common primary glomerulonephritis triggered by mucous membrane alteration; however, there is a discussion about vaccination-caused IgA flare [2]. The immunological nature of IgAN and misleading information in public sources leaves patients skeptical about whether to get vaccinated [3]. The study aimed to investigate the impact of SARS-CoV-2 vaccination on the clinical course of IgA nephropathy. METHOD: Adult patients treated in Pauls Stradins Clinical University Hospital with morphologically proven IgAN were included in the study. Patients with secondary IgAN were excluded. Evaluation of clinical and laboratory markers was performed on inclusion visit and on the second visit 6 months later. SARS-CoV-2 vaccination type and status were noted on both visits. Estimated GFR was calculated with CKD-EPI creatinine-cystatin equation. IBM SPSS Statistics version 27 and Microsoft Excel 10 were used for data analysis. RESULTS: The study involved 54 patients, 36 were unvaccinated and 18 were fully vaccinated. A significant difference between the two groups was observed by baseline proteinuria. Other differences were not observed. Fourteen patients were vaccinated with mRNA vaccine, 13 with Comirnaty and 1 with Spikevax, and four patients were vaccinated with Vaxzevria vector vaccine. The differences between the two groups are shown in Table 1. During study period, two patients had COVID-19 infection; a patient in the vaccinated group had COVID-19 prior to vaccination. CONCLUSION: SARS-CoV-2 vaccination did not affect the clinical course of IgA nephropathy. Our study results indicate that SARS-CoV-2 vaccination in IgA nephropathy patients was safe regarding renal function and disease activity markers. (Table Presented).publishersversionPeer reviewe

    Leucine-Rich Alpha-2-Glycoprotein (LRG-1) as a Potential Kidney Injury Marker in Kidney Transplant Recipients

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    Publisher Copyright: © Ann Transplant, 2022;.Background: Material/Methods: Results: Conclusions: Kidney transplantation is the treatment of choice for most patients with end-stage renal disease. To improve patient and transplant survival, non-invasive diagnostic methods for different pathologies are important. Leucine-rich alpha-2-glycoprotein (LRG-1) is an innovative biomarker that is elevated in cases of angiogenesis, inflammation, and kidney injury. However, there are limited data about the diagnostic role of LRG-1 in kidney transplant recipients. The aim of this study was to evaluate the association between serum LRG-1, urine LRG-1, and kidney transplant function and injury. We enrolled 35 kidney transplant recipients in the study. LRG-1 in the serum and urine was detected using ELISA. We evaluated the correlation of serum and urine LRG-1 with traditional serum and urine kidney injury markers. A higher level of serum LRG-1 correlates with a higher level of urine LRG-1. Serum LRG-1 has a positive correlation with transplant age, serum urea, serum creatinine, serum cystatin C, proteinuria, and fractional excretion of sodium (FENa) and a negative correlation with hemoglobin and estimated glomerular filtration rate (eGFR). Urine LRG-1 has a positive correlation with serum cystatin C, proteinuria, and urine neutrophil gelatinase-as-sociated lipocalin (NGAL). Higher levels of serum and urine LRG-1 are associated with kidney transplant injury and functional deterioration. Thus, LRG-1 might be also as a biomarker for tubular dysfunction in patients after kidney transplantation.publishersversionPeer reviewe

    Relatório de estágio em farmácia comunitária

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    Relatório de estágio realizado no âmbito do Mestrado Integrado em Ciências Farmacêuticas, apresentado à Faculdade de Farmácia da Universidade de Coimbr

    Annotation of verbal valency in Latvian

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    Development of valency resource for Latvian was started recently. The chosen approach takes into account the experience of other projects dealing with verbal valency (such as FrameNet for English, the valency dictionary of Lithuanian by N. Sližienė and Vallex for Czech) and is supplemented with our own ideas. The article describes our approach to the verbal valency annotation – the valency types (syntactic, semantic valency, selectional restrictions), the set of the semantic roles, and presents the tool developed for the valency annotation. Initially two annotation layers are chosen – semantic valency (semantic roles) and syntactic valency – the morphological description of the dependents of the verbs. The valency models (combinations of semantic roles) are generated from the annotated core semantic roles only. Non-core semantic roles are not used in this process because they are not specific enough to particular verbs. In future the annotation of one more valency layer is planned – very general ontological categories (animate, inanimate, abstract object, physical object, human) will be added. An online tool is developed for manual annotation of valences within a pre-selected corpus. The valency models, as well as morphological forms corresponding to each semantic role are suggested automatically. Summarized information of the valency of each verb, as well as a corpus of annotated sentences will be available as a result of the project. Currently valency of approx. 180 verbs (more than 25 000 utterances) is annotated using data from the Balanced Corpus of Modern Latvian

    Patstāvīgās vārdšķiras formālā latviešu valodas analīzē

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    CONTENT WORDS IN THE FORMAL ANALYSIS OF LATVIANSummaryTo characterize morphological features of each word in a text, a set of morphological features for Latvian has been defined. It describes grammatical categories and their pos­sible values characteristic of a particular part of speech or a smaller group of words.To define this set it was necessary to clarify several grammatical categories of content words due to fact that their description in the existing grammars of Latvian differs or is not sufficiently explicated.Morphological features of pronouns and verbs are discussed in detail.Regarding pronouns, the main issues are the nominal categories (gender, number and case) and the category of person. A table with a full list of Latvian pronouns and their grammatical categories is offered.Regarding verbs, the problematic categories are tense (for debitive and conditional forms) and person (for debitive, relative and conditional forms), as well as the category of number for the third person verbs.</p

    Dictionary and Thesaurus of Latvian - Tezaurs.lv (ELEXIS)

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    Tēzaurs.lv: An extensive dictionary and thesaurus of Latvian, comprising more than 320,000 lexical entries, including multi-word units. Compiled and edited based on more than 300 sources. Provides detailed morphological information; being extented into a Latvian WordNet

    Universal Dependencies 2.0 alpha (obsolete)

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    This release contains errors in several files. Please use http://hdl.handle.net/11234/1-1983 instead
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